Środowiskowe Seminarium z Informacji i Technologii Kwantowych
sala 1.03, ul. Pasteura 5
Radek Łapkiewicz (IFD UW)
ODWOLANE/CANCELED. What can photon pair detection do for super-resolution microscopy and phase imaging?
Quantum imaging typically requires the preparation of fragile states of light with which the sample is illuminated. An entirely different scheme, in which the sample itself “prepares” the quantum state required for imaging, was proposed and demonstrated by Schwartz and colleagues [1, 2]. Their quantum correlation microscopy method relies on photon antibunching and allows improving the resolution by the factor of \sqrt(2), beyond the diffraction limit. This is achieved by replacing the standard intensity measurement with the measurement of the number of photon pairs which are missing due to photon antibunching. In general, n-th order correlations, provide the resolution improvement by the factor of \sqrt(n). Interestingly, most of the fluorophores used in microscopy exhibit photon antibunching and, as a consequence, can be used in quantum correlation microscopy. Recently, this method has been combined with image scanning microscopy, a super-resolution microscopy technique, and used to obtain super-resolved images of a biological sample [3]. A classical analog of the quantum correlation microscopy turned out to offer a similar resolution improvement and required measurement times shorter by an order of magnitude [4].
We will introduce the basics of quantum and classical correlation microscopy and discuss its implementations. The second part of the talk will be devoted to interferometric phase imaging enabled by photon correlation measurements.
Interferometric methods are essential for making precise measurements and typically require high coherence between the measured and the reference beam. When the phase offset between the two beams changes randomly, the interferogram averages out, erasing all the spatial phase information. We will show that, even when the lowest order interference fringes cannot be observed, spatial phase of a beam can be measured. This is achieved by spatially resolved photon counting and the analysis of a photon pair detection probability distribution [5]. These results demonstrate that information contained in photon correlations enables phase imaging in conditions in which traditional methods fail.
[1] O. Schwartz, D. Oron, Improved resolution in fluorescence microscopy using quantum correlations, Phys. Rev. A 85, 033812 (2012).
[2] O. Schwartz et al. Superresolution microscopy with quantum emitters, Nano Lett. 13, 5832–5836 (2013).
[3] R. Tenne, et al., Super-resolution enhancement by quantum image scanning microscopy, Nat. Phot., 13, 116–122 (2019).
[4] A. Sroda, et al., Super-resolution optical fluctuation image scanning microscopy (SOFISM), arXiv:2002.00182 (2020).
[5] J. Szuniewicz et al., Noise Resistant Phase Imaging with Intensity Correlation, Rochester Conference on Coherence and Quantum Optics (2019).
We will introduce the basics of quantum and classical correlation microscopy and discuss its implementations. The second part of the talk will be devoted to interferometric phase imaging enabled by photon correlation measurements.
Interferometric methods are essential for making precise measurements and typically require high coherence between the measured and the reference beam. When the phase offset between the two beams changes randomly, the interferogram averages out, erasing all the spatial phase information. We will show that, even when the lowest order interference fringes cannot be observed, spatial phase of a beam can be measured. This is achieved by spatially resolved photon counting and the analysis of a photon pair detection probability distribution [5]. These results demonstrate that information contained in photon correlations enables phase imaging in conditions in which traditional methods fail.
[1] O. Schwartz, D. Oron, Improved resolution in fluorescence microscopy using quantum correlations, Phys. Rev. A 85, 033812 (2012).
[2] O. Schwartz et al. Superresolution microscopy with quantum emitters, Nano Lett. 13, 5832–5836 (2013).
[3] R. Tenne, et al., Super-resolution enhancement by quantum image scanning microscopy, Nat. Phot., 13, 116–122 (2019).
[4] A. Sroda, et al., Super-resolution optical fluctuation image scanning microscopy (SOFISM), arXiv:2002.00182 (2020).
[5] J. Szuniewicz et al., Noise Resistant Phase Imaging with Intensity Correlation, Rochester Conference on Coherence and Quantum Optics (2019).