Konwersatorium im. J.Pniewskiego i L.Infelda
sala 0.06, ul. Pasteura 5
2024-03-04 (11:00) 
dr hab. Beata Brzozowska (Wydział Fizyki UW)
DNA damage and repair in cells exposed to radiation
DNA is the fundamental molecule encoding and storing the genetic information of all living organisms. DNA damage and repair is by essence a multidisciplinary line of research, and it is one of the main topics of medical physics studies performed in Radiobiological Laboratory at Faculty of Physics, University of Warsaw. The genetic material is a labile substance that is constantly damaged either spontaneously or due to the action of DNA damaging agents like ionising radiation.
During colloquium I will discuss the results of experiments performed with cells exposed to radiations, which differ in the way how interactions are distributed inside a nucleus. While X-rays are sparsely ionizing, alpha particles hit cells in a highly condensed manner, as single tracks. A combined exposure places the cell in a particularly difficult situation of experiencing both hit scenarios which leads to the formation of clustered damage posing serious problems for the DNA repair machinery.
During colloquium I will discuss the results of experiments performed with cells exposed to radiations, which differ in the way how interactions are distributed inside a nucleus. While X-rays are sparsely ionizing, alpha particles hit cells in a highly condensed manner, as single tracks. A combined exposure places the cell in a particularly difficult situation of experiencing both hit scenarios which leads to the formation of clustered damage posing serious problems for the DNA repair machinery.
Pobierz plakat / Download the poster
Pobierz slajdy / Download the slides
Obejrzyj nagranie / Watch the video